PERQUE Glucose Regulation Guard Forté is a natural and comprehensive solution to these problems. Enhanced glucose regulation means more energy, improved immune defense and repair, lower risk of glucose dysregulation, fewer side effects, increased patient satisfaction, and compliance resulting in better outcomes. PERQUE Glucose Regulation Guard Forté produces rapid benefits without reported adverse effects associated with oral hypoglycemic drugs.*

50,000 Americans are at risk. Glucose dysregulation is epidemic and induces:

• coronary and atherosclerotic disease
• accelerated aging
• sexual dysfunction
• chronic fatiguability
• obesity and weight control problems
• impaired immune defense and repair.*

Safely lowers weight, increases energy, and improves lean body mass.*

Maintaining blood sugar balance requires efficient delivery of glucose to cells for energy. PERQUE Glucose Regulation Guard Forté regulates blood sugar (blood glucose) levels by enhancing glucose transport activity.*

Diet, weight, and exercise are essential for healthy blood glucose levels. However, because it is difficult for most people to maintain ideal diet and exercise programs, a natural aid can help.* Blood glucose-lowering (oral hypoglycemic) medications are often prescribed. Benefits are often marginal, and a host of side effects are noted in the latest Physicians Desk Reference (PDR), including gastrointestinal problems, impairment of B-12 and other essential nutrients absorption, metabolic/lactic acidosis, and kidney problems. Additionally, these drugs often lose effectiveness over time and can exacerbate the sexual dysfunction commonly seen in diabetics. PERQUE Glucose Regulation Guard Forté offers a better choice that avoids these adverse effects.

Corosolic acid is derived from the Banaba plant (Lagerstroemia speciosa) and has a powerful glucose-lowering and insulin uptake function. Corosolic acid has been successfully used to manage the symptoms of diabetes and has a weight loss benefit.

Galega officinalis (French lilac). The Galega officinalis plant has been known since the Middle Ages for relieving the symptoms of diabetes mellitus. The active ingredient in this plant that lowers blood sugar by decreasing insulin resistance is galegine or isoamylene guanidine. Chemical derivatives from galegine include metformin from the biguanide class of antidiabetic medications, which was approved by the FDA in1995.

Bitter melon/marah (Momordica charantia). Bitter melon is a plant related to the Chinese cucumber. It is commonly consumed as a vegetable in Asia and has long been used as an adjunct in diabetes management. Additionally, it has antibacterial and anti-parasitic properties. Bitter melon also has the potential to down-regulate insulin and is also thought to slow the aging process.

Huckleberry/bilberry (Vaccinium myrtillus). Huckleberry / Bilberry has been used traditionally in the treatment of diabetes, and research suggests that its leaf extract can lower blood sugar levels.

Chromium citrate and vanadium ascorbate in their most potent forms. Chromium is needed for blood sugar metabolism, improving glucose tolerance, and helps lower body weight while increasing lean body mass. Vanadium enhances sugar metabolism and reduces the need for insulin in both Type I and Type II diabetics.*

Agnus castus (Chaste tree berry) in PERQUE Glucose Regulation Guard Forté at a full 250 mg. of high activity material improves HPA axis function, enhancing the often overlooked but important hormonal influence on blood glucose. Hormonal dysregulation and distress increases risk from and complications of Metabolic Syndrome/ insulin resistance. Diabetes becomes more brittle and difficult to control when hormonal dysregulation exists.

Ensuring blood glucose balance is critical for anyone seeking to restore or maintain good health, and is particularly indicated for the following conditions:*
• Metabolic Syndrome /Insulin resistance management – The group of symptoms including high blood pressure and increased cardiovascular risk, high cholesterol and triglyceride levels, and obesity are referred to as Metabolic Syndrome or insulin resistant syndromes. Underlying this metabolic disturbance are persistent elevations in blood glucose and insulin levels that have been shown to precede Type II diabetes.*
• Type I diabetes - Balanced blood sugar with PERQUE Glucose Regulation Guard Forté may help insulin dependent diabetics reduce their need for insulin.*
• Type II diabetes – Risk increases with age, weight, and decreased physical activity. Using PERQUE Glucose Regulation Guard Forté as a primary supplement to maintain blood sugar balance, along with dietary control and regular exercise, may reduce or eliminate the need for insulin or glucose lowering medications and help prevent the kidney, eye, and heart damage associated with poor glucose control.*
• Weight management/obesity - Because excess blood glucose from impaired carbohydrate metabolism signals fat cells to store lipids, resulting in weight gain, PERQUE Glucose Regulation Guard Forté can modify carbohydrate metabolism, both promoting weight loss and preventing weight gain (or regain).*

REFERENCES
1. Hadden DR. Goat’s rue - French lilac - Italian fitch - Spanish sainfoin: gallega officinalis and metformin: The Edinburgh connection. JR Coll Physicians Edinb 2005 Oct;35(3):258-60.
2. Jaffe R. Metabolic Management of Syndrome X. Comprehensive Care Seminar, September 14, 2000.
3. McCarty MF. Does bitter melon contain an activator of AMPactivated kinase? Med Hypotheses 2004;63(2):340-3.
4. Meigs JB, et al. Hyperinsulinemia, Hyperglycemia, and Impaired Homeostasis. JAMA 2000; 283: 221- 228.
5. Rosmond R, Dallman MF, Bjorntorp P. Stressrelated cortisol secretion in men: relationships with abdominal obesity and endocrine, metabolic and hemodynamic abnormalities. J Clin Endocrinol Metab 1998; 83(6):1853-9.1.
6. Savickiene N, Dagilyte A, Lukosius A, and Zitkevicius V. Importance of biologically active components and plants in the prevention of complications of diabetes mellitus. Medicina (Kaunas) 2002; 38(10):970-975.
7. Witters LA. The blooming of the French lilac. J Clin Invest 2001;108:1105–1107.
8. Zavaroni I, Bonini L, Fantuzzi M, Dall’Aglio E, Passeri M, Reaven GM. Hyperinsulinemia, obesity, and syndrome X. J Intern Med 1994; 235(1):51-6.
9. Fukushima M, Matsuyama F, Ueda N, Egawa K, etal. Effect of corosolic acid on postchallenge plasma glucose levels. Diabetes Res Clin Pract. 2006 Aug;73(2):174-7.